BIEN 545. Diagnostic Devices at the Point-of-Care.

The fundamental of diagnosis devices from design concepts to implementation in real-life application, a brief review of the gold standard diagnostic methods and their limitations, the building blocks of an ideal diagnostic device with a focus on point-of-care applications, biomolecular recognition elements including different one-step and multi-step assays based on nucleic acids and proteins, and the fundamental of sample delivery systems and fluid flow based on microfluidics, the integration of bioassays and microfluidics in lab-on-chip devices for automated sample preparation and detection, real-life application of lab-on-chip devices in medical diagnosis and the commercialized approaches.