CHEM 542. Advanced Nucleic Acid Chemistry.

Advanced-level chemical reactivity and metal binding properties, advanced methods for synthesis, purification and characterization of DNA/RNA, non-canonical DNA/RNA structures and functions, self-assembly of functional nucleic acid-based materials, chemical and fluorescence-based methods for probing nucleic acids in vitro and in vivo, in vitro evolution of functional nucleic acids for biotechnology, and diagnostic and therapeutic applications of modified nucleic acids.