PHAR 565. Epigenetic Drugs and Targets.

This course covers therapeutics targeting epigenetic mechanisms. Although only a handful of epigenetic drugs are in widespread use, further development of such agents is a very active area of research as it has the potential to directly target aberrant gene expression. This course will examine both the current use and potential of epigenetic drugs in treatment of cancer, neurological diseases, immune disorders, and cardiovascular disease. The concept of epigenetics as mediating gene-environment interaction will also be discussed.