DENT 688. Bone Mechanobiology .

Foundational theories in mechanobiology in the context of skeletal tissues (namely, bone, growth plate cartilage, and periodontal tissues). Brief introduction to structure- function relations in bone, mechanical strain, and fluid flow. Emphasis is placed on the concepts of bone adaptation to biomechanical loading patterns, mechanobiology at the tissue level and mechanotransduction at the cellular level. Research methodologies and applications to disease are discussed.