Clinical and Translational Research (EXMD)

Physiology and Biochemistry Endocrine Systems.

Terms offered: Winter 2026

Offered in conjunction with the Department of Physiology. The course provides a basic knowledge of endocrine systems encompassing biosynthesis, metabolism and physiological actions of hormones. Specific topics covered are hormones of the hypothalamus, pituitary, adrenals, thyroids, parathyroids, pancreas, gut and the gonads. The role of hormones and growth factors in pregnancy and fetal development are also discussed.

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Clinical Applications of Regenerative Medicine.

Terms offered: this course is not currently offered.

Principles of stem cell translational research. Advanced training in the development of clinical applications of new technologies through rigorous clinical standards in different areas of regenerative medicine.

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Advanced Endocrinology 1.

Terms offered: this course is not currently offered.

This course is designed for U3 students who are in a major or honours program in anatomy, biology, biochemistry or physiology and for graduate students. A multidisciplinary approach will be used to teach biosynthesis and processing of hormones, their regulation, function and mechanism of action. The material will cover hypothalamic, pituitary, thyroid, atrial and adrenal hormones as well as prostaglandins and related substances.

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Advanced Endocrinology 02.

Terms offered: Winter 2026

Study of the parathyroids, gut and pancreatic hormones and growth factors. In addition, the role of hormones and growth factors in reproduction and fetal maturation will be discussed.

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Biology of Cancer.

Terms offered: this course is not currently offered.

An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.

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Directed Readings in Regenerative Medicine .

Terms offered: Winter 2026

The literature pertaining to a proposed field of research involving stem cell biology and/or clinical translation will be explored in collaboration with an approved faculty mentor.

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Advanced Applied Cardiovascular Physiology.

Terms offered: this course is not currently offered.

Offered in conjunction with the Department of Physiology. Current topics, methods and techniques for studying the cardiovascular system. Basic and applied cardiac electrophysiology, mechanisms of pacemaker activity, arrhythmias, the effects of drugs on cardiac functions, fetal circulation, coronary circulation, mechanics of blood flow, cardiovascular diseases, renal and neural control of the circulation, and cardiac assist devices.

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Advanced Applied Respiratory Physiology.

Terms offered: this course is not currently offered.

Offered in conjunction with the Department of Physiology. In depth coverage of respiratory biology including: functional anatomy of the respiratory system, pulmonary statics and dynamics, chest wall and respiratory muscles, ventilation and perfusion, control of breathing, and defense mechanisms. This course is aimed at providing a solid grounding in pulmonary biology and its research applications.

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Advanced Topics in Respiration.

Terms offered: Winter 2026

Offered in conjunction with the Department of Physiology. In depth coverage of developmental physiology, pulmonary vascular physiology, biology of airway smooth muscle, respiratory epithelium and molecular biology of respiratory muscles. Dyspnea, mechanical ventilation and respiratory failure will also be covered. This course emphasizes application of respiratory biology to basic and applied research and touches on pulmonary pathophysiology.

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Gastrointestinal Physiology and Pathology.

Terms offered: Winter 2026

Course deals with various aspects of gastrointestinal and hepatic function in health and altered physiological states. The principal focus is on the recent literature pertaining to cell and molecular mechanisms underlying the motility secretory process, absorption and secretion. The molecular biology of the hepatic viruses and various aspects of colonic neoplasia will also be considered.

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Bioanalytical Separation Methods.

Terms offered: this course is not currently offered.

The student will be taught the capabilities and limitations of modern separation methods (gas and high-performance liquid chromatography, capillary electrophoresis, hyphenated techniques). Application of these techniques to solve analytical problems relevant to biomedical research will be emphasized, with special attention being paid to the processing of biological samples.

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Joint Venturing with Industry.

Terms offered: Winter 2026

Using problem-based learning, the course examines the various business interactions between researchers and their business partners in support and development of research into commercial endeavours using models such as venture capital, business partnerships, or grants-in-aid.

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